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Group 2 innate lymphoid cells (ILC2s) are central mediators of airway hyperreactivity
Absolute ethanol, dimethyl sulfoxide (DMSO), crystal violet, methanol, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) were obtained from Shanghai Macklin Biochemical Co., Ltd
The researchers showed that blocking glutamine metabolism through JHU083 not only suppressed tumor cell metabolism but also mitigated the tumor microenvironment, which is hostile to the immune response due to its hypoxic, acidic, and nutrient-depleted conditions, unleashing the natural antitumor T cell response
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L., Bammler T
10.1164/rccm.200504-594OC
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