Astaxanthins molecular structure enables it to neutralize both fat-soluble and water-soluble free radicals
Cells were incubated for 2 h at 37 C
Neurological diseases can disrupt iron absorption and transport, leading to excessive iron accumulation, increased oxidative stress, and resulting in cellular ferroptosis
When your body is under relentless oxidative attack, your glutathione reserves can get depleted faster than your body can rebuild them
References Alikhani N, Ankarcrona M, Glaser E (2009) Mitochondria and Alzheimers disease: amyloid-beta peptide uptake and degradation by the presequence protease, hPreP
Additionally, the FRAP assay does not measure thiol-based antioxidants like glutathione and primarily evaluates reducing capacity based on the ferric ion, which is not directly linked to the mechanistic or physiological relevance of antioxidant activity