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Four decades ago, researchers made a stunning discovery: the existence of a hormone called glucagon-like peptide 1 (GLP-1)

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It gets harder to keep a calorie deficit when alcohol is involved

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Similarly, in the von Frey test, mice injected with intraplantar vehicle after CFA induction displayed slow recovery of mechanical allodynia

But true receptor downregulation through lysosomal degradation requires the cell to synthesize entirely new receptors, a process that takes considerably longer