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Despite rapid advances in the design of Erastin analogs and derivatives, the fundamental problem of on-target toxicity remains unresolved

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Data extraction was conducted independently by two reviewers using standardized templates

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We look forward to working with Ascendis to explore the potential of the TransCon technology platform to reduce the dosing frequency of GLP-1 receptor agonists and other treatments for cardiometabolic diseases. GLP-1 treatments are a class of diabetes and obesity medications that mimic a hormone that regulates blood sugar and suppresses appetite