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Critically, this region contains the highest predicted Local Distance Difference Test (pLDDT) scores (the degree of confidence of an amino acid and all surrounding amino acids) throughout the R-domain

935 Mechanistically, elabela interacts to APJ, activating the Nrf2/ARE pathway through guanine nucleotide binding protein alpha 13 subunit (G13)

doi: 10.1016/j.jada.2010.03.018 131

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