These studies focused mainly on weight loss and how safe the drug is over time
[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Zeman F., Koller M., Figueiredo R., Aazevedo A., Rates M., Coelho C., Kleinjung T., de Ridder D., Langguth B., Landgrebe M
In the subgroups of patients with T2DM and received SEM as the third-line therapy (add-on to MET + TZD or MET + SU), treatment with either dose of SEM for 30 weeks to 56 weeks was associated with greater reduction in BMI, compared with SIT, EXE, or IG (Table 32)
Following the May 1, 2026 authorization of a second generic, from Apotex, seven other generic semaglutide submissions from different companies remain under review, with regulatory decisions expected in the coming weeks and months [Source: canada.ca/en/health-canada/news/2026/05/canada-approves-second-generic-semaglutide-the-first-g7-country-to-do-so.html]
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Irwin, N