what is more effective for weight loss semaglutide or tirzepatide vs Semaglutide: Which Drug Best Tirzepatide vs Semaglutide - GLP-1

No trial has tested all three together

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The indirect effects, mediated through reductions in HbA1c and body weight, appeared to explain 45.9% [95% CI 20.771.0%] of the decrease in UACR associated with tirzepatide relative to the pooled comparator and driven primarily by improved glycemic control, with no statistically significant role for weight reduction