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Using RT, we were able to monitor the dynamic changes of GSH in living cells, which subsequently led to the observation of enhanced antioxidant capability of activated neurons and time-dependent changes of GSH during the ferroptosis process

Hong, D

Its derivative, 4-octyl itaconate (4-OI), activates the Nrf2 pathway by alkylating Keap1, thereby inducing antioxidant enzymes such as HO-1 and NQO1 to scavenge reactive oxygen species and alleviate oxidative stress in SLE