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Participants reported improvements in mobility, physical activity capacity, and energy levels throughout treatment despite substantial weight reduction

It is dosed around 1.6 mg daily, subcutaneously

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Zhang Y, Chen H, Feng Y, Liu M, Lu Z, Hu B, Chen L, Zhang Y, Liu J, Cai F, Zhao Y, Pan W, Liao X, Pan S, Bestard-Lorigados I, Wu Y, Song W (2025) Activation of AMPK by GLP-1R agonists mitigates Alzheimer-related phenotypes in transgenic mice