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Then, how do tumor cells sustain rapid proliferation when a large portion of glutamine is shunted toward GSH synthesis via GGCT-mediated regulation, consequently reducing glutamine flux into TCA cycle

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Short-term antioxidant effects 2

However, its levels naturally decline with age, and obtaining sufficient amounts through diet alone can be challenging

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coli , we reduced the reported disulfide bond between the active site cysteine C13 and GSH in the clarified cell lysate using dithiothreitol (DTT) and removed the reduced GSH with an extended on-column washing step during purification