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Not because it is the only thing that matters, but because it is the system most consistently disrupted, the system most accessible to functional medicine intervention, and the system whose healing most reliably opens the door to gains in every other domain
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Teens with pre-existing kidney conditions or those with diabetes/blood sugar dysregulation should strictly avoid creatine unless directed otherwise by a specialist, as it can affect kidney filtration markers and blood glucose management
Research has also implicated GLP-1R activation in the CNS with neuroprotective effects in Alzheimers disease models, but also suggests that neuropsychological symptoms such as depression can be exacerbated through GLP-1R activation
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