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The supplementation significantly reduced participants weight, body mass index (BMI), total cholesterol, blood sugar, insulin, and systolic blood pressure

Nat Med 2024;30:205866

Preparation during the easy weeks is what separates completers from quitters

Unlike semaglutide, which targets only the GLP-1 receptor, tirzepatide is a dual-action medication that activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

18 Myth : GLP-1 drugs are unsafe with numerous side effects

The use of prazosin, an 1-adrenergic receptor blocker, showed that the ability of GLP-1RAs to reduce TNF- in plasma was disrupted, signifying the vital role of 1-adrenergic receptors in the anti-inflammatory action of GLP-1RAs