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SchiattarellaGGSanninoAToscanoEGiuglianoGGargiuloGFranzoneAet alGut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis

Inhibition of miR-192 leads to increased expression of stearoyl-CoA desaturase 1 (SCD-1), the enzyme that catalyzes the biosynthesis of monounsaturated fatty acids [317], resulting in increased TG accumulation

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The UPF additives can disrupt the gut microbial environment (76)

Moreover, these CD11c+ macrophages release pro-inflammatory markers such as TNF-a, IL-6, C-reactive protein (CRP), and monocyte chemotactic protein-1 (MCP-1), all of which exacerbate inflammation (55