Chen Y, Li X, Yang M, Liu S-B
If the drug has too great an effect in the upper GI system, it can cause nausea, as happens when eating a huge meal too fast
Endocrine Connections, 6 (8), 647-658
This means reactions may appear after multiple doses rather than necessarily with first exposure, as the immune system requires time to develop a response to the medication
Crucially, this decrease was primarily attributable to a reduction in candy consumption, while chow intake increased compared to vehicle-treated controls with access to both food types (Raun et al., 2007)
In brief, data are collected retrospectively at first visit and prospectively whenever the patient returns for scheduled follow-up (at least every 3 months) or unscheduled visits with neurologists and neuro-ophthalmologists specialized in IIH