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By 2030, JP Morgan estimates that 35% of diabetes patients and 15 million obese individuals in the U.S

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GLP-1 Agonists for Type 2 Diabetes and Weight Loss

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BV2 cells pre-polarized into M0, M1, and M2 phenotypes were used as controls

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In these cases, switching to a different glucose-lowering agent or stopping metformin altogether may improve tolerability

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Other studies found no significant difference from placebo

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