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[PubMed: 23259606] 259

Boucher W, Kempuraj D, Cao J, Papaliodis D, Theoharides TC

This shift toward a higher serotonin-to-dopamine ratio can result in a subtle blunting of the reward response

The peptide stimulates an increase in NAD+, a cellular metabolism cornerstone, activating the sirtuin-1 gene, often dubbed the longevity gene

Based on this evidence, the c-MET axis has been exploited as an intriguing therapeutic target for drug development in different types of tumor