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METHODS Data source and study population The Optum Labs Data Warehouse database contains longitudinal, de-identified administrative claims and electronic health record (EHR) data on enrollees and patients, representing a mixture of ages and geographical regions across the US

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Similarly, some authors observed that metformin users had a lower clinical severity of TC at presentation and a longer disease free survival in metastatic patients (Jang et al., 2015), while other authors did not observe any difference in the risk of developing metastases when compared with non-treated patients (Noh et al., 2019)

Tominaga K, Hongo N, Karato M, Yamashita E

This position has been vigorously contested by compounding pharmacy industry groups and individual pharmacies