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these effects are dose-dependent and resolve with dose reduction

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Traverso N, Ricciarelli R, Nitti M, et al

I personally use 1 gram (2 caps) in the morning upon rising and 1 gram at night before bed to support my adrenal health, circulation, and immune system function

A recent article postulates that supporting nitric acid metabolism with certain medications or supplements could ameliorate sickle cell disease symptoms

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