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In contrast, CR-fed females not only had reduced plaques, but had reduced glial activation relative to both CR and DL-fed mice, with substantially lower pro-inflammatory gene expression, suggesting that while caloric reduction alone may attenuate plaque pathology, the reduction in plaque deposition observed in the DL-fed mice may not be mediated by glial cells

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Glutathione, -L-glutamyl-L-cysteinyl-glycine, is a tripeptide present in every cell of the human body [7]

The references above describe laboratory and animal research and are provided for scientific context only