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BDNF mimetic 7,8-dihydroxyflavone rescues rotenone-induced cytotoxicity in cardiomyocytes by ameliorating mitochondrial dysfunction
The different organs including heart, liver, spleen, lung, and kidney were collected, washed and then homogenized in 1.0 mL of lysis buffer with superfine homogenizer
Gozes group has found that ADNP mutations affect MT dynamics and inhibit its interactions with Tau [348, 349], producing a tauopathy-like phenotype manifested in increased GSK-3 activity, Tau hyper-phosphorylation, and cognitive deficiency [293]
Cellular quality control by the ubiquitin-proteasome system and autophagy
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