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[44] reported that SOCS1 and SOCS3 inhibited the signaling of insulin receptor by inducing a ubiquitin-mediated degradation of IRS1 and IRS2 proteins (Fig

The latter is consistent with the pseudotime analysis of our scRNA-seq data, showing that Vegfc expression is initiated in Esm1 + ECs during early steps of arterial specification and prior to Bmx expression (Supplementary Fig

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