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Ipamorelin acts through GHS-R1a/Gq/phospholipase C/IP/calcium signalling in pituitary somatotrophs a pathway mechanistically distinct from and complementary to the GHRH-R/cAMP pathway engaged by CJC-1295 Without DAC

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Oral formulations of GLP-1 agonists exist but show reduced efficacy compared to injectable versions

The peptide also suppresses inflammatory genes like TNF-alpha that speed up aging

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