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Mitochondrial DNA in innate immune responses and inflammatory pathology

This characteristic has made it an interesting molecule for exploratory studies in regenerative medicine, sports science, and biotechnology research

It sits right next to the "furnace" where energy is produced, placing it on the front lines of cellular stress

doi: 10.3390/healthcare9091118 59

In general, they are master antioxidants important in aging and dark skin

It also plays an essential role in folate and related one-carbon metabolism, where FAD is required as a cofactor for methylenetetrahydrofolate reductase (MTHFR), a key folate-metabolizing enzyme