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Synbiotic supplementation, systemic inflammation, and symptoms of brain disorders in elders: a secondary study from a randomized clinical trial

The augmentation of serotonin synthesis by vitamin D may act in a complementary manner to SSRIs, whose mechanism of action is predominantly the inhibition of serotonin reuptake.This dual mechanism is hypothesised to result in the optimisation of serotonergic activity and the enhancement of clinical outcomes.In comparison to SSRIs, vitamin D offers several advantages

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However, many liver specialists and updated guidelines recommend a conservative cap of 3,000mg, especially if you are using it for several days running

Yokozawa T, Kim YJ

However, potential side effects can include: Nausea or dizziness (rare) Headaches Injection site irritation Overstimulation or fatigue if overdosed There are no long-term human trials, so effects on hormones, organs, or chronic use remain unknown