GLP-1RAs can suppress foam cell formation by activating GLP-1R signaling induced autophagy [134], reducing ACAT1 expression/activity [93], as well as inhibiting the PKA/CD36 pathway to inhibit ox-LDL uptake [135]
A practical lab rule is to remove the vial only for the time needed, keep the septum clean, withdraw carefully, then return it to refrigeration
If you are struggling to meet minimum nutritional needs, your provider or a dietitian can help you develop strategies
Asahara N, et al
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This was a GLP-1-based therapy, mechanistically, that did not influence cardiovascular risk