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It promotes weight loss by reducing appetite and calorie intake, which is a positive outcome for many people with type 2 diabetes or obesity

Targeted action of small molecule drugs remains a challenge in medicine

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Clinical trial data on weight regain The STEP-10 extension trial revealed that participants who stopped semaglutide regained over 40% of their lost weight within just 28 weeks

Sotk, M., Clark, M., Suur, B

[7] Commonly observed adverse effects include transient injection-site discomfort, breast tenderness, nausea, fluid retention, and mild mood fluctuation, whereas rarer but serious events encompass venous or arterial thromboembolism, gallbladder disease, significant elevation of blood pressure, and hormone-sensitive malignancies such as endometrial or breast cancer