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Impact of GLP-1 receptor agonists on psoriasis and cardiovascular comorbidities: a narrative review
Patients with a history of cholecystectomy (gallbladder removal) face no additional gallstone risk from GLP-1 therapy, as they have no gallbladder to form stones
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Whether this unique pattern worsens the obese state or constitutes a favorable adaptation remains unclear, and the physiological and pathophysiological implications of the altered GH/IGF-I axis in obesity remain uncertain with GH neither being the cause nor the solution to reverse obesity
Indeed, the Step Up trial showed that some people benefit from a higher weekly dose, resulting in an average weight loss of 20.7% over 72 weeks
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