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In addition to the glucoregulatory and central appetite-suppressive effects of GLP-1 receptor agonists, this drug class also exhibit gastrointestinal effects by inhibiting gastric emptying as well as having intestinotrophic and gut immunomodulatory properties 18,19,20,21,22

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The samples were subsequently reprecipitated with TCA, and a mixture of deuterated IS for every marker was added, including [2H8]Lys (d8-Lys), [2H5]5-hydroxy-2-aminovaleric acid (d5-HAVA), a stable derivative for GSA

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