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The risk of renal adverse reactions was increased in patients with a history of renal impairment (the weight management trials included 65 patients with a history of moderate or severe renal impairment at baseline), and occurred more frequently during dose titration

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Liver injury was also found in about 10% of chronic abusers of ketamine

Gene sequencing indicated an -thalassemia minor and that probably masked the megaloblastic features of vitamin B 12 deficiency