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A systematic review and network meta-analysis of 483 full-text articles compared GLP-1RAs and placebo for weight loss

However, it can also cause side effects like nausea, vomiting, constipation, or stomach upset

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By 1989 the Copehnagen researchers had managed to complete the full sequence for porcine peptide and confirmed the sequence for the human peptide originally predicted by Bell in 1983

Nausea, mild diarrhea, reduced appetite, and fatigue are most frequent during weeks 13, typically resolving as the body adjusts

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