Some dose-dependent increases were observed at higher doses compared to placebo, but these remained within normal ranges and did not indicate pathological C-cell stimulation
This means that if someone takes Xanax for a long time, their body might get used to it, making it harder to stop taking the medication
37 CKD Trials CREDENCE and DAPA-CKD are seminal randomized controlled trials which specifically evaluated the effect of SGLT2 inhibitors on a primary kidney end point and ultimately provide the strongest evidence for use in patients with CKD (Table 2)
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