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The leached amount would be attributed to the poor association/adsorption of a small fraction of the AuNCs with/at the surface of PLGA in resemblance to the known burst release of encapsulated drugs in PLGA nanohosts
To develop a precise treatment approach, it is essential to delve deeper into the active constituents of Chinese herbal medicine, identify the specific components associated with relevant intestinal microbiota and their metabolites, and conduct comprehensive experimental investigations for thorough validation
(2019) examined the impact of PD medications (levodopa and entacapone) on gut microbiota, finding marked changes in Peptoniphilus, Finegoldia, Faecalibacterium, Fusicatenibacter, Anaerococcus, Bifidobacterium, Enterococcus , and Ruminococcus
This pathway inhibits the lipid peroxidation and reduces highly toxic lipid peroxides to protect cells from oxidative damage through glutathione catalysis