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Sepesi B, Correa AM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Ajani JA, Walsh GL, Swisher SG , Hofstetter WL

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The proteome concentration of lysates was normalized to 2 mg/mL, and 100 L was transferred to a LoBind Eppendorf tube containing 48 mg of urea

Therefore, Golgi stress induces this iron-dependent RCD presumably via the prooxidant/antioxidant balance impairment [170]

Despite their promise, significant challenges remain, including optimizing formulations, ensuring safety and efficacy across diverse populations, and achieving successful clinical translation