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Like the plot of a 2000s teen movie, GLP-1 medications are like the main character who starts at a new school and becomes popular overnight

There is also a more subtle risk worth knowing: the Pasqua 2025 trial reported two cases of euglycemic ketosis without acidosis in semaglutide-treated participants

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These are common during the initial weeks as your body adjusts to the medication

Retatrutide is widely studied as a triple receptor agonist, engaging GLP-1, GIP, and glucagon pathways linked to metabolic regulation, appetite signalling, energy balance, glucose metabolism, lipid utilisation, and body composition research