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Studies with treatment with GLP-1 analogues in type 2 diabetes have found that the initial postprandial insulin is increased after treatment, and this has been misinterpreted as evidence for a GLP-1 mediated insulin stimulation [28]

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The primary outcome was analyzed using an analysis of covariance with treatment as fixed effect, and baseline BMI stratum and baseline energy intake as covariates

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Are injection site reactions more common with tirzepatide or semaglutide