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Because severe COVID-19 could reflect immune dysregulation, a benefit and/or lack of adverse effects in patients receiving plasma from convalescent individuals might reflect the suppression of inflammation induced by IgG, rather than supporting the conclusion that passive antibodies do not trigger ADE of disease through Fab- or Fc-dependent mechanisms

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When function improves, pain often becomes less dominant

doi:10.1016/j.urology.2015.05.046