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253,254 Therefore, chemical modification at this specific position could improve siRNA binding affinity

The World Health Organization (WHO) projects that global obesity prevalence will increase from 14% in 2020 to 25% by 2035 , affecting nearly 1.9 billion individuals

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Furthermore, as it will be further discussed, we have reported a neuroprotective role for IGFs associated to mitochondrial protection and antioxidant defenses in aging animals[5558]

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