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While many media reports tout the remarkable effectiveness of GLP-1 drugs (and their great expense) for weight loss, few address the serious side effects associated with their use, such as loss of skeletal muscle (and the risk of sarcopenia) and bone mineral density (and the risk of osteomalacia and osteoporosis), and the weight gain that typically follows their discontinuation

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Oxidative stress was introduced using hydrogen peroxide to simulate reactive cellular environments