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The therapy was shown to be safe, well tolerated and possibly beneficial for symptoms

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Hwang J, Kiick KL, Sullivan MO

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MIA, an inhibitor of glyceraldehyde-3-phosphate dehydrogenase, can disrupt chondrocyte glycolysis and ultimately lead to cell death, thereby contributing to cartilage degradation, subsequent alterations in subchondral bone, and the development of osteophytes 25,34