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CYP2E1 oxidation generates reactive oxygen species (ROS) as byproducts

NY State J Med 79:22, 1979

The screening identified 24 compounds, of which EA, 10058-F4, cryptotanshinone, ZM 39923, and PRT 4165 were cytotoxic to breast cancer cell lines while simultaneously displaying cancer cell selectivity

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In brief, the mice were administered a daily topical application of 62.5 mg of 5% imiquimod cream (Mingxinlidi, Sichuan, China) on their shaved backs for seven consecutive days