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Although clinical trials can provide powerful evidence to evaluate the efficacy of novel drugs, their ability to draw definitive conclusions about drug safety is limited due to the finite scope, restricted time frame, strict study entry criteria, and relatively small sample sizes

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A comprehensive search of electronic databases such as PubMed, Web of Science, and Cochrane Library, was conducted to find pertinent studies reporting on the frequency and severity of gastrointestinal symptoms in type 2 diabetes patients receiving tirzepatide

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So in the evening, you're forced to deal with hunger without the stimulant crutch