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Anthony Brissett attributed the demand to fat disappearing from the face faster than skin adapts, describing patient complaints of hollowed cheeks, increased skin laxity, and more pronounced jowls

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Although benign in most cases, NAFLD may also evolve to more aggressive phenotypes, including nonalcoholic steatohepatitis (NASH) with or without fibrosis, cirrhosis, liver failure and hepatocellular carcinoma (HCC), which render NAFLD a serious public health concern, if considering the high global prevalence of the disease [3]

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