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With declining estrogen, you become more prone to losing lean mass and storing fat, especially around the midsection

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Specifically, fatty acid metabolism (normalized enrichment score (NES) = 1.66), oxidative phosphorylation (OxPhos

When taking these supplements in combination, research suggests an optimal pairing of 2 grams L-citrulline with 2 grams L-arginine for maximising nitric oxide production

Journal of Clinical Investigation, 134(2)