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I-02 The protease inhibitor Inter--trypsin inhibitor heavy chain 4 (ITIH4) as a compensatory inhibitor in plasma of hereditary angioedema patients Steffen Thiel Department of Biomedicine, Aarhus University, Denmark Allergy, Asthma & Clinical Immunology 2025, 21(Suppl 2) :I-02 Inter--trypsin inhibitor heavy chain 4 (ITIH4) is a regulator of plasma proteolytic systems, with growing evidence linking it to both health and disease

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Since pharmacokinetic data of the short-acting formulation of Ex applied in the present study is only available for rodents [35] and humans [36] (but not rhesus macaques), the timing of the drug administration and the two sessions was determined based on the behavioural findings of Scott and Moran [22], where the dose-dependent anorectic effects of Ex in rhesus macaque operant food consumption was seen up to 6 h post-administration

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Research observations include: Restoration of natural testosterone production Improved sperm quality Enhanced reproductive cellular function These findings remain under active investigation in laboratory settings