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We found that the amount of AngIV in mouse tissue increased after the administration of Dihexa compared to that in the WT group

To view a copy of this licence, visit About this article Cite this article Bosco, F., Giai Via, R., Giustra, F

Given the mechanism of enzyme inhibition, our non-covalent inhibitors can be targeted to TrxR and can be applicable to development of therapeutics for a broad range of diseases

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The study's single-blind design and placebo control add credibility, but the very small sample size means the results should be interpreted cautiously

In vitro investigations illustrate that SPINs efficiently suppress the activation of cGAS/STING in macrophages, curbing the production of IFNI and impeding STINGmediated M1 polarization