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In SURMOUNT-1, tirzepatide reached 20.9% mean weight loss at 72 weeks on the highest-dose arm (n=2,539)

DOI: 10.1038/s41591-026-04416-4

While most heart palpitations are not dangerous, there are times when they could be a sign of a more serious health problem

Treatment begins with a low dose that may be adjusted over time based on your response and tolerance

Lyophilized powder freezes fine for long-term storage, but once a peptide is in solution, ice crystals physically damage the structure you lose potency and get precipitation on thaw

Virtually every contemporary drug-related crime Ive seen in the pharmaceutical space has been tried in the GLP-1 space over the last five years