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Furthermore, the presence of PGP at the peptide's C-terminus might also modify its interactions with specific transporters or receptors on the BBB, potentially favoring its transport via receptor-mediated transcytosis

Prostate carcinogenesis: inflammatory storms

For weight loss experiments over a two week period, standard laboratory chow was replaced with HFD for four weeks to generate a diet-induced obese (DIO) mice that were then maintained on HFD and injected intraperitoneally every 48 hours with candidate drugs or vehicle (DMSO

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Borrego F, Alonso MC, Galiani MD, Carracedo J, Ramirez R, Ostos B, et al

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