While rare, persistent severe abdominal pain, complete loss of bowel function for 5+ days, or acute bloating can indicate obstruction or other complications requiring medical attention
A full medication review should be completed before initiating treatment
At the end of 2016, the Amgen team filed a patent (US20170275370A1) titled "Methods for Treating or Ameliorating Metabolic Disorders Using a GIPR Binding Protein in Combination with a GLP-1 Agonist." This reported the therapeutic potential of using an antibody targeting the GIPR in combination with a GLP-1 receptor agonist for the treatment of type 2 diabetes, obesity, dyslipidemia, elevated levels of glucose, increased insulin levels, and diabetic nephropathy
This interview has been edited and condensed.
Martucci, L
Taking too much can cause side effects like nausea, headache, dizziness, and, in some cases allergic reactions