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Within preclinical investigative frameworks, laboratory studies may examine peptidemetal binding interactions, structural stability, solution behavior following reconstitution, and intracellular signaling responses associated with copper-dependent biochemical pathways

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doi:10.1016/j.watres.2011.09.008 Calza P, Sakkas VA, Villioti A et al (2008) Multivariate experimental design for the photocatalytic degradation of imipramine