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The most frequently reported symptoms include: Nausea (especially during dose increases) Vomiting Diarrhea Constipation Abdominal discomfort Decreased appetite (an expected effect of the medication) For most patients, side effects stay in the tolerable range and tend to taper off as treatment continues

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The practical answer is to take it with food, not on an empty stomach, unless your prescriber gives different instructions

Journal of applied physiology 88 , 14741480 (2000)

Many of these earlier studies were based on the hypothesis that IPF is an inflammatory disorder